BDBM50062614 CHEMBL900::Dimethyl-[2-(phenyl-o-tolyl-methoxy)-ethyl]-amine::Disipal::Invagesic::N,N-dimethyl-2-(phenyl(o-tolyl)methoxy)ethanamine::Norflex::Norgesic::ORPHENADRINE::Orphengesic

SMILES CN(C)CCOC(c1ccccc1)c1ccccc1C

InChI Key InChIKey=QVYRGXJJSLMXQH-UHFFFAOYSA-N

Data  10 KI  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50062614   

TargetHistamine H1 receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50062614(CHEMBL900 | Dimethyl-[2-(phenyl-o-tolyl-methoxy)-e...)
Affinity DataIC50:  9.77E+4nMAssay Description:Antagonist activity at H1 receptor in human HeLa cells assessed as inhibition of histamine-induced Ca2+ release by using fura-2AM-based fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistamine H1 receptor(RAT)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50062614(CHEMBL900 | Dimethyl-[2-(phenyl-o-tolyl-methoxy)-e...)
Affinity DataIC50:  162nMAssay Description:Displacement of [3H]mepyramine from histamine H1 receptor in Sprague-Dawley rat brain membrane after 2 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed